ALDH3B1

Across TCGA pan-cancer cohorts, ALDH3B1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ALDH3B1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ALDH3B1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ALDH3B1 expression acts as an unfavorable survival marker.

PDAC, COAD, and CCRCC are the cancer types where ALDH3B1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	III,IV	0.536	0.971	<.001	36	view →
COAD	DFS	Median	All	0.840	1.000	.030	30	view →
CCRCC	DFS	Quartile	III,IV	0.233	0.830	.038	7	view →
HNSC	DFS	Median	All	0.299	0.782	.028	5	view →
LUAD	DFS	Quartile	III,IV	0.440	0.925	.041	3	view →
UCEC	DFS	Median	All	0.795	0.928	.045	2	view →
GBM	OS	Quartile	All	0.417	0.661	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ALDH3B1–PDAC (OS)

Open the PDAC breakdown →