ALDH3B1

Across TCGA cell cohorts, ALDH3B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,375 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ALDH3B1-associated GO terms across cancer lineages are Regulation of actin filament polymerization, Membrane raft assembly, and Regulation of protein localization to cell periphery. Each is linked with ALDH3B1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ALDH3B1-to-partner and partner-to-ALDH3B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament polymerization grouped by ALDH3B1-low versus ALDH3B1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDH3B1→partner) and Y-score (partner→ALDH3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of actin filament polymerization →	+0.121	+3.257	<.001	<.001	3	14
LIVER	Membrane raft assembly →	+0.213	+2.636	<.001	.002	3	14
BONE	Regulation of protein localization to cell periphery →	+0.103	+3.755	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of protein localization to membrane →	+0.088	+2.881	.001	<.001	3	14
BONE	Toll-like receptor 7 signaling pathway →	+1.233	+3.079	<.001	<.001	3	14
BONE	Positive regulation of CD4-positive, alpha-beta T cell activation →	+0.109	+2.378	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,375 associations by consensus.

Regulation of actin filament polymerization by ALDH3B1 expression — OESOPHAGUS

Explore this box plot interactively →