Across TCGA cell cohorts, AKR7L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,026 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AKR7L-associated GO terms across cancer lineages are Mycotoxin catabolic process, Aflatoxin catabolic process, and Toxin catabolic process. Each is linked with AKR7L in more than 17 cancer types. Because this analysis shows association rather than direction, both AKR7L-to-partner and partner-to-AKR7L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR7L→partner) and Y-score (partner→AKR7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mycotoxin catabolic process →	-0.245	-0.838	<.001	<.001	3	18
BREAST	Aflatoxin catabolic process →	-0.245	-0.838	<.001	<.001	3	18
BLOOD_Myeloma	Toxin catabolic process →	-0.166	-0.531	.001	.002	3	13
BLOOD_Myeloma	Mycotoxin metabolic process →	-0.201	-0.588	<.001	<.001	3	12
BLOOD_Myeloma	Aflatoxin metabolic process →	-0.201	-0.588	<.001	<.001	3	12
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.171	+0.703	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,026 associations by consensus.

Exploration

AKR7L survival (RNA) · tumor vs normal (RNA) · all AKR7L data types