AKR1B1P8

Across TCGA patient cohorts, AKR1B1P8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,711 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AKR1B1P8-associated GO terms across cancer lineages are Positive regulation of nervous system development, Lipid homeostasis, and Positive regulation of cold-induced thermogenesis. Each is linked with AKR1B1P8 in more than 4 cancer types. Because this analysis shows association rather than direction, both AKR1B1P8-to-partner and partner-to-AKR1B1P8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of nervous system development grouped by AKR1B1P8-low versus AKR1B1P8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKR1B1P8→partner) and Y-score (partner→AKR1B1P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of nervous system development →	+0.064	+0.025	<.001	<.001	3	5
STAD	Lipid homeostasis →	+0.074	+0.028	<.001	<.001	3	5
STAD	Positive regulation of cold-induced thermogenesis →	+0.084	+0.028	<.001	<.001	3	5
STAD	Nucleoside phosphate biosynthetic process →	+0.115	+0.027	<.001	<.001	3	5
STAD	Organic acid transmembrane transport →	+0.064	+0.030	<.001	<.001	3	5
STAD	Regulation of epithelial cell apoptotic process →	+0.075	+0.026	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,711 associations by consensus.

Positive regulation of nervous system development by AKR1B1P8 expression — STAD

Explore this box plot interactively →