Q-omics provides the consensus-scored AKR1B1P8 profile across patient tissues and cancer cell-line models. AKR1B1P8 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in MESO. Additionally, AKR1B1P8 RNA expression shows 5,711 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight MESO, and STAD as cancer lineages where AKR1B1P8 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes AKR1B1P8 survival associations across molecular data types. AKR1B1P8 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

AKR1B1P8 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	MESO (108)	view →

This table ranks reproducible AKR1B1P8 RNA expression–survival associations across cancer types. High AKR1B1P8 expression shows unfavorable associations in MESO, LUAD, STAD, KIRP and UCEC, but favorable associations in ACC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for AKR1B1P8 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.069	0.580	<.001	108	view →
LUAD	OS	Tertile	III,IV	0.147	0.679	.001	57	view →
ACC	OS	Tertile	III,IV	1.000	0.318	.008	54	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	27	view →
KIRP	DFS	Tertile	II,III,IV	0.122	0.626	.032	27	view →
UCEC	DFS	Tertile	All	0.300	0.671	.022	24	view →

Pink = unfavorable, green = favorable. all 9 lineages →

AKR1B1P8-MESO (OS)

Kaplan–Meier survival curve for AKR1B1P8 RNA expression in MESO: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with AKR1B1P8 in patient tissues and cancer cell lines. In patient samples, AKR1B1P8 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,711	STAD (5516)	view →
RNA	4,291	COAD (1935)	view →