AKIRIN1

Across TCGA cell cohorts, AKIRIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,624 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AKIRIN1-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Heterochromatin organization, and Myoblast migration involved in skeletal muscle regeneration. Each is linked with AKIRIN1 in more than 14 cancer types. Because this analysis shows association rather than direction, both AKIRIN1-to-partner and partner-to-AKIRIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by AKIRIN1-low versus AKIRIN1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AKIRIN1→partner) and Y-score (partner→AKIRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Establishment of protein localization to organelle →	+0.047	+0.995	<.001	<.001	3	15
OVARY	Heterochromatin organization →	+0.069	+0.750	<.001	<.001	3	14
BLOOD_Lymphoma	Myoblast migration involved in skeletal muscle regeneration →	+0.202	+0.873	<.001	<.001	3	14
BREAST	Nuclear pore complex assembly →	+0.171	+1.223	<.001	<.001	3	13
BONE	DNA-templated transcription initiation →	+0.075	+0.661	.007	.007	1	15
KIDNEY	Nucleocytoplasmic transport →	+0.076	+0.777	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,624 associations by consensus.

Establishment of protein localization to organelle by AKIRIN1 expression — BLOOD_Myeloma

Explore this box plot interactively →