AKAP8L

Across TCGA patient cohorts, AKAP8L RNA expression is significantly associated with the RNA expression of many other genes, with 19,974 significant associations in total. ACC shows the largest number of these associations.

The most reproducible AKAP8L-associated genes across cancer lineages are CCDC130, GMEB2, and CENPT. Each is linked with AKAP8L in more than 33 cancer types. Because this analysis shows association rather than direction, both AKAP8L-to-partner and partner-to-AKAP8L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP8L versus CCDC130 in ACC, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP8L→partner) and Y-score (partner→AKAP8L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	CCDC130 →	+0.970	+1.065	<.001	<.001	3	34
SCLC	GMEB2 →	+0.773	+0.691	<.001	<.001	3	33
KIRC	CENPT →	+1.085	+0.834	<.001	<.001	3	33
KIRC	SNRNP70 →	+1.171	+0.831	<.001	<.001	3	33
ACC	MED26 →	+0.901	+1.153	<.001	<.001	3	33
ACC	AKAP8 →	+0.896	+1.034	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,974 associations by consensus.

AKAP8L vs CCDC130 — ACC

Explore this scatter interactively →