AKAP8L

Across TCGA patient cohorts, AKAP8L protein abundance is significantly associated with the RNA expression of many other genes, with 16,308 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AKAP8L-associated genes across cancer lineages are OVOL3, ATAD2, and NCAPD2. Each is linked with AKAP8L in more than 6 cancer types. Because this analysis shows association rather than direction, both AKAP8L-to-partner and partner-to-AKAP8L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AKAP8L versus OVOL3 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP8L→partner) and Y-score (partner→AKAP8L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	OVOL3 →	+0.554	+0.304	<.001	<.001	3	7
GBM	ATAD2 →	+1.032	+0.296	<.001	<.001	3	7
HNSC	NCAPD2 →	+1.058	+0.229	.006	.001	3	7
GBM	FANCB →	+0.892	+0.247	<.001	<.001	3	7
GBM	VRK1 →	+0.820	+0.308	<.001	<.001	3	6
HNSC	IGF2BP3 →	+1.820	+0.259	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,308 associations by consensus.

AKAP8L vs OVOL3 — GBM

Explore this scatter interactively →