Across TCGA patient cohorts, AKAP14 mutation is significantly associated with the RNA expression of many other genes, with 349 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AKAP14-associated genes across cancer lineages are SNORD109B, RNU6-883P, and OFD1P4Y. Each is linked with AKAP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both AKAP14-to-partner and partner-to-AKAP14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AKAP14→partner) and Y-score (partner→AKAP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNORD109B →	+0.541	+6.324	<.001	.001	3	2
UCEC	RNU6-883P →	+0.524	+2.663	.004	<.001	3	2
STAD	OFD1P4Y →	+0.030	+5.147	.001	.001	3	2
UCEC	IGKV1OR2-118 →	+0.174	+2.206	.005	.001	3	1
UCEC	TAF9 →	+0.519	+3.480	.001	.002	3	1
UCEC	IGHV2-70 →	+1.739	+3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 349 associations by consensus.

Exploration

AKAP14 survival (RNA) · tumor vs normal (RNA) · all AKAP14 data types