Q-omics provides the consensus-scored SNORD109B profile across patient tissues and cancer cell-line models. SNORD109B expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, SNORD109B RNA expression shows 5,326 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where SNORD109B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes SNORD109B survival associations across molecular data types. SNORD109B RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

SNORD109B data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	HNSC (48)	view →

This table ranks reproducible SNORD109B RNA expression–survival associations across cancer types. High SNORD109B expression shows unfavorable associations in HNSC, SKCM, STAD, BLCA, LIHC and KIRC. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .010). Together, the overview and detailed table identify HNSC as the clearest survival context for SNORD109B RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.245	0.609	.010	48	view →
SKCM	DFS	Tertile	II,III,IV	0.134	0.712	<.001	45	view →
STAD	OS	Tertile	IV	0.074	0.496	.002	36	view →
BLCA	OS	Tertile	IV	0.018	0.600	<.001	36	view →
LIHC	OS	Tertile	All	0.144	0.688	.013	27	view →
KIRC	OS	Tertile	II,III,IV	0.219	0.536	.036	12	view →

Pink = unfavorable, green = favorable. all 9 lineages →

SNORD109B-HNSC (OS)

Kaplan–Meier survival curve for SNORD109B RNA expression in HNSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with SNORD109B in patient tissues and cancer cell lines. In patient samples, SNORD109B shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,326	STAD (5107)	view →
RNA	5,073	BRCA (2368)	view →