AIRN

Across TCGA patient cohorts, AIRN RNA expression is significantly associated with the go_rna of many other GO terms, with 6,980 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AIRN-associated GO terms across cancer lineages are Regulation of cellular response to heat, Regulation of telomere maintenance, and Regulation of microtubule-based process. Each is linked with AIRN in more than 20 cancer types. Because this analysis shows association rather than direction, both AIRN-to-partner and partner-to-AIRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cellular response to heat grouped by AIRN-low versus AIRN-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AIRN→partner) and Y-score (partner→AIRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of cellular response to heat →	+0.068	+0.082	<.001	<.001	3	21
STAD	Regulation of telomere maintenance →	+0.064	+0.101	<.001	<.001	3	20
STAD	Regulation of microtubule-based process →	+0.044	+0.096	<.001	<.001	3	20
STAD	Protein-containing complex disassembly →	+0.058	+0.090	<.001	<.001	3	20
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.059	+0.086	<.001	<.001	3	20
STAD	Modulation by host of viral process →	+0.058	+0.088	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,980 associations by consensus.

Regulation of cellular response to heat by AIRN expression — ESCA

Explore this box plot interactively →