AIRN

Across TCGA pan-cancer cohorts, AIRN RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of AIRN’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where AIRN RNA is more highly expressed in tumor relative to normal tissue. In most cancer types AIRN is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

STAD, HNSC, and KIRC are the cancer types where AIRN tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AIRN RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	II,III,IV	+0.042	<.001	5	view →
HNSC	Male	II,III,IV	+0.009	.014	4	view →
KIRC	All	IV	−0.010	.030	2	view →
COAD	All	All	+0.014	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

AIRN–STAD

Open the STAD breakdown →