AIRN

Across TCGA pan-cancer cohorts, AIRN RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated AIRN data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher AIRN RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated AIRN expression acts as an unfavorable survival marker, although some lineages such as CESC and STAD show a favorable association.

CESC, DLBC, and STAD are the cancer types where AIRN RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	II,III,IV	0.696	0.324	.009	24	view →
DLBC	OS	Median	III,IV	0.272	1.000	.017	22	view →
STAD	OS	Median	IV	0.642	0.194	.003	21	view →
UVM	OS	Tertile	III,IV	0.204	0.707	.023	15	view →
MESO	OS	Tertile	III,IV	0.315	0.586	.016	15	view →
READ	OS	Tertile	All	1.000	0.461	.020	12	view →
THYM	DFS	Quartile	III,IV	0.492	0.749	.014	10	view →
COAD	DFS	Quartile	II,III,IV	0.381	0.603	.015	9	view →
SARC	OS	Tertile	All	0.408	0.677	.009	9	view →
LIHC	DFS	Tertile	All	0.448	0.563	.036	9	view →
KIRC	OS	Tertile	All	0.550	0.684	.018	8	view →
SKCM	OS	Tertile	III,IV	0.803	0.654	.011	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

AIRN–CESC (DFS)

Open the CESC breakdown →