AHSG

Across TCGA cell cohorts, AHSG RNA expression is significantly associated with the go_rna of many other GO terms, with 2,708 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AHSG-associated GO terms across cancer lineages are Negative regulation of cholesterol import, Muscle organ development, and Nucleoside phosphate biosynthetic process. Each is linked with AHSG in more than 8 cancer types. Because this analysis shows association rather than direction, both AHSG-to-partner and partner-to-AHSG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cholesterol import grouped by AHSG-low versus AHSG-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AHSG→partner) and Y-score (partner→AHSG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of cholesterol import →	+2.176	+5.652	<.001	<.001	3	9
BONE	Muscle organ development →	-0.123	-0.678	<.001	.001	3	5
LIVER	Nucleoside phosphate biosynthetic process →	+0.066	+5.469	.003	.003	3	5
LIVER	Positive regulation of natural killer cell differentiation →	-1.341	-8.422	<.001	<.001	3	5
OVARY	T cell activation involved in immune response →	+0.108	+0.234	<.001	.001	3	5
BONE	Parathyroid gland development →	-1.370	-1.017	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,708 associations by consensus.

Negative regulation of cholesterol import by AHSG expression — LIVER

Explore this box plot interactively →