AHR

Across TCGA patient cohorts, AHR RNA expression is significantly associated with the RNA expression of many other genes, with 19,469 significant associations in total. UVM shows the largest number of these associations.

The most reproducible AHR-associated genes across cancer lineages are TGFBR2, CMTM6, and CPD. Each is linked with AHR in more than 32 cancer types. Because this analysis shows association rather than direction, both AHR-to-partner and partner-to-AHR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AHR versus TGFBR2 in THYM, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHR→partner) and Y-score (partner→AHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	TGFBR2 →	+1.807	+1.571	<.001	<.001	3	33
THYM	CMTM6 →	+1.352	+1.535	<.001	<.001	3	33
THYM	CPD →	+1.296	+1.521	<.001	<.001	3	32
SCLC	NCOA3 →	+1.449	+1.144	<.001	<.001	3	32
UVM	RAP1B →	+1.076	+1.136	<.001	<.001	3	32
SCLC	VPS13C →	+1.597	+1.074	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,469 associations by consensus.

AHR vs TGFBR2 — THYM

Explore this scatter interactively →