AHCYL2

Across TCGA patient cohorts, AHCYL2 protein abundance is significantly associated with the protein abundance of many other proteins, with 18,967 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AHCYL2-associated proteins across cancer lineages are RFC4, RRP36_S73, and SMC2. Each is linked with AHCYL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AHCYL2-to-partner and partner-to-AHCYL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AHCYL2 versus RFC4 in GBM, with a Pearson correlation of -0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AHCYL2→partner) and Y-score (partner→AHCYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RFC4 →	-0.452	-0.545	<.001	<.001	3	7
LSCC	RRP36_S73 →	-1.005	-0.447	<.001	<.001	3	7
GBM	SMC2 →	-0.561	-0.503	<.001	<.001	3	7
UCEC	BAZ2A_S1783 →	-0.977	-0.360	<.001	<.001	3	7
LSCC	TOP2A →	-1.061	-0.441	<.001	<.001	3	7
LSCC	CDK1 →	-0.774	-0.485	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,967 associations by consensus.

AHCYL2 vs RFC4 — GBM

Explore this scatter interactively →