AGAP2-AS1

Across TCGA cell cohorts, AGAP2-AS1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AGAP2-AS1-associated genes across cancer lineages are BPIFA1, FAM205A, and C16orf96. Each is linked with AGAP2-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP2-AS1-to-partner and partner-to-AGAP2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFA1 grouped by AGAP2-AS1-low versus AGAP2-AS1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP2-AS1→partner) and Y-score (partner→AGAP2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFA1 →	+0.109	+3.103	.005	.004	3	1
LARGE_INTESTINE	FAM205A →	+0.020	+4.029	<.001	.001	3	1
LARGE_INTESTINE	C16orf96 →	+0.519	+3.520	.003	.005	3	1
CNS	HES3 →	+0.041	+5.321	<.001	.005	3	1
LARGE_INTESTINE	SH3GL2 →	+1.461	+3.252	<.001	.009	2	1
LARGE_INTESTINE	TKTL2 →	+0.045	+3.187	<.001	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

BPIFA1 by AGAP2-AS1 expression — LARGE_INTESTINE

Explore this box plot interactively →