AGAP2-AS1

Across TCGA pan-cancer cohorts, AGAP2-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated AGAP2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher AGAP2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated AGAP2-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and LIHC show a favorable association.

ACC, MESO, and KIRP are the cancer types where AGAP2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.408	0.843	<.001	166	view →
MESO	OS	Median	All	0.396	0.689	<.001	120	view →
KIRP	OS	Tertile	III,IV	0.205	0.697	<.001	84	view →
BLCA	DFS	Tertile	All	0.184	0.534	<.001	83	view →
KIRC	OS	Median	All	0.543	0.709	<.001	72	view →
LGG	DFS	Median	All	0.634	0.835	<.001	54	view →
COAD	DFS	Median	IV	0.342	0.648	.003	41	view →
UVM	DFS	Quartile	III,IV	1.000	0.165	.006	37	view →
SKCM	OS	Median	All	0.256	0.405	<.001	31	view →
THCA	OS	Median	III,IV	0.898	0.989	.005	18	view →
GBM	OS	Tertile	All	0.316	0.499	.007	15	view →
LIHC	DFS	Median	III,IV	0.547	0.247	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

AGAP2-AS1–ACC (OS)

Open the ACC breakdown →