AGAP1

Across TCGA patient cohorts, AGAP1 mutation is significantly associated with the RNA expression of many other genes, with 5,514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGAP1-associated genes across cancer lineages are RCC1, TOMM22, and ZWINT. Each is linked with AGAP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AGAP1-to-partner and partner-to-AGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RCC1 grouped by AGAP1-low versus AGAP1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP1→partner) and Y-score (partner→AGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RCC1 →	+0.744	+3.750	.001	<.001	3	4
STAD	TOMM22 →	+0.512	+3.635	<.001	.001	3	4
UCEC	ZWINT →	+0.710	+2.321	<.001	<.001	3	4
UCEC	TIPIN →	+0.527	+1.731	<.001	<.001	3	4
UCEC	TRMU →	+0.372	+2.031	<.001	<.001	3	4
UCEC	GOT1 →	+0.462	+1.951	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,514 associations by consensus.

RCC1 by AGAP1 expression — STAD

Explore this box plot interactively →