AGAP1

Across TCGA pan-cancer cohorts, AGAP1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of AGAP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where AGAP1 RNA is repressed in tumor relative to normal tissue. In most cancer types AGAP1 is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

KICH, LIHC, and CHOL are the cancer types where AGAP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AGAP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.371	<.001	9	view →
LIHC	Female	II,III,IV	+1.286	<.001	9	view →
CHOL	All	All	+2.374	<.001	5	view →
BLCA	Male	IV	−1.620	.010	5	view →
BRCA	Female	All	−0.288	<.001	4	view →
COAD	All	All	−0.259	.005	4	view →
PRAD	All	All	+0.552	<.001	2	view →
KIRC	Female	All	+0.421	.019	2	view →
STAD	Male	II,III,IV	+0.747	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

AGAP1–KICH

Open the KICH breakdown →