AGAP1-IT1

Across TCGA patient cohorts, AGAP1-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,544 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AGAP1-IT1-associated proteins across cancer lineages are AGAP1_S521, SH3BP1, and IGHG1. Each is linked with AGAP1-IT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both AGAP1-IT1-to-partner and partner-to-AGAP1-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGAP1-IT1 versus AGAP1_S521 in GBM, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP1-IT1→partner) and Y-score (partner→AGAP1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AGAP1_S521 →	+0.426	+0.690	<.001	<.001	3	5
HNSC	SH3BP1 →	-0.244	-0.731	<.001	.002	3	4
GBM	IGHG1 →	-0.532	-0.725	<.001	<.001	3	4
GBM	LCP2 →	-0.364	-0.601	<.001	<.001	3	4
LSCC	MBD3 →	+0.460	+0.572	.002	.002	3	4
GBM	TRIM24 →	+0.332	+0.584	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,544 associations by consensus.

AGAP1-IT1 vs AGAP1_S521 — GBM

Explore this scatter interactively →