AFDN-DT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AFDN-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 13,273 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AFDN-DT-associated proteins across cancer lineages are AFDN, AFDN_S1275, and AFDN_S246. Each is linked with AFDN-DT in more than 8 cancer types. Because this analysis shows association rather than direction, both AFDN-DT-to-partner and partner-to-AFDN-DT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AFDN-DT→partner) and Y-score (partner→AFDN-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVAFDN →+0.423+0.987<.001<.00139
BRCAAFDN_S1275 →+0.856+0.472.003.00435
OVAFDN_S246 →+0.664+0.737.001.00235
BRCADNAJC1 →-0.485-0.438<.001<.00135
GBMDOK3 →-0.480-0.414<.001<.00134
GBMEVI2B →-0.588-0.613<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,273 associations by consensus.

Exploration