AFAP1-AS1

Across TCGA patient cohorts, AFAP1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,984 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AFAP1-AS1-associated proteins across cancer lineages are TRIM2, PRPF4, and ATR_S435. Each is linked with AFAP1-AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AFAP1-AS1-to-partner and partner-to-AFAP1-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AFAP1-AS1 versus TRIM2 in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AFAP1-AS1→partner) and Y-score (partner→AFAP1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRIM2 →	+0.735	+1.163	<.001	<.001	3	3
GBM	PRPF4 →	+0.251	+0.426	.002	.001	3	3
LSCC	ATR_S435 →	-0.541	-0.971	<.001	.005	3	3
BRCA	DUSP12 →	+0.288	+0.917	.001	.002	3	3
HNSC	HERC4 →	-0.209	-1.170	<.001	<.001	3	3
BRCA	IL4I1 →	+0.738	+1.321	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,984 associations by consensus.

AFAP1-AS1 vs TRIM2 — BRCA

Explore this scatter interactively →