ADTRP

Across TCGA patient cohorts, ADTRP mutation is significantly associated with the RNA expression of many other genes, with 1,485 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADTRP-associated genes across cancer lineages are ANKRD20A6P, MIR6737, and SNORD30. Each is linked with ADTRP in more than 1 cancer types. Because this analysis shows association rather than direction, both ADTRP-to-partner and partner-to-ADTRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD20A6P grouped by ADTRP-low versus ADTRP-high in OV.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADTRP→partner) and Y-score (partner→ADTRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANKRD20A6P →	+0.262	+5.906	<.001	.002	3	2
BRCA	MIR6737 →	+0.524	+5.506	<.001	.005	3	2
UCEC	SNORD30 →	+0.799	+1.830	.006	.008	3	2
BRCA	MIR548AL →	+0.417	+6.505	<.001	.001	3	2
BRCA	RN7SL14P →	+0.215	+5.317	<.001	.006	3	2
SKCM	TRIM60P13 →	+0.027	+4.302	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,485 associations by consensus.

ANKRD20A6P by ADTRP expression — OV

Explore this box plot interactively →