ADIG

Across TCGA cell cohorts, ADIG RNA expression is significantly associated with the mutation status of many other genes, with 184 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADIG-associated genes across cancer lineages are MT-ND5, ZNF43, and DOCK10. Each is linked with ADIG in more than 1 cancer types. Because this analysis shows association rather than direction, both ADIG-to-partner and partner-to-ADIG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT-ND5 grouped by ADIG-low versus ADIG-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIG→partner) and Y-score (partner→ADIG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MT-ND5 →	+4.000	+0.073	<.001	<.001	3	2
CNS	ZNF43 →	+2.730	+0.267	.008	<.001	3	2
BLOOD_Leukemia	DOCK10 →	+3.762	+0.010	.007	<.001	3	2
BLOOD_Leukemia	SLC24A1 →	+4.569	+0.015	.003	<.001	3	2
LUNG_SCLC	TMC6 →	+5.029	+0.065	.006	<.001	3	2
LARGE_INTESTINE	HPCA →	+4.977	+0.038	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

MT-ND5 by ADIG expression — SOFT_TISSUE

Explore this box plot interactively →