ADIG

Across TCGA pan-cancer cohorts, ADIG RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated ADIG data layer compared with 1 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher ADIG RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ADIG expression acts as an unfavorable survival marker, although some lineages such as CESC and SCLC show a favorable association.

DLBC, LGG, and CESC are the cancer types where ADIG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	72	view →
LGG	OS	Median	All	0.332	0.521	<.001	54	view →
CESC	DFS	Tertile	All	0.844	0.710	.021	42	view →
KIRC	DFS	Median	All	0.723	0.835	.007	38	view →
SCLC	DFS	Tertile	II,III,IV	1.000	0.349	.022	9	view →
THYM	OS	Median	II,III,IV	0.840	1.000	.023	4	view →
LUSC	OS	Median	IV	0.851	0.255	.036	3	view →
PCPG	OS	Quartile	All	0.774	0.980	.018	3	view →
KIRP	DFS	Median	III,IV	0.825	0.453	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

ADIG–DLBC (OS)

Open the DLBC breakdown →