ADGRL1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADGRL1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,861 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADGRL1-associated genes across cancer lineages are MEIS3, ASPA, and RERG. Each is linked with ADGRL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADGRL1-to-partner and partner-to-ADGRL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRL1 versus MEIS3 in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRL1→partner) and Y-score (partner→ADGRL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEIS3 →+1.037+0.372<.001<.00133
GBMASPA →+0.970+0.357<.001<.00133
UCECRERG →+1.843+0.500<.001<.00133
UCECNTRK3 →+0.720+0.444.001.00133
UCECRSPO3 →+1.113+0.447<.001<.00133
GBMTCEAL2 →+0.893+0.310<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,861 associations by consensus.

ADGRL1 vs MEIS3 — UCEC

Per-sample scatter of ADGRL1 vs MEIS3 in UCEC (Pearson r = 0.48).

Explore this scatter interactively →

Exploration