ADGRG7

Across TCGA patient cohorts, ADGRG7 protein abundance is significantly associated with the RNA expression of many other genes, with 211 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ADGRG7-associated genes across cancer lineages are MAN2B1, TMEM147, and LSM5. Each is linked with ADGRG7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRG7-to-partner and partner-to-ADGRG7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRG7 versus MAN2B1 in PDAC, with a Pearson correlation of -0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG7→partner) and Y-score (partner→ADGRG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MAN2B1 →	-0.362	-1.105	.006	<.001	3	1
PDAC	TMEM147 →	+0.206	+0.910	.005	.008	3	1
PDAC	LSM5 →	+0.808	+1.385	.009	.006	3	1
PDAC	AUP1 →	+0.485	+1.522	.004	.007	3	1
PDAC	RALGPS2 →	+1.268	+1.473	.002	.002	3	1
PDAC	SCAMP3 →	+0.325	+0.946	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 211 associations by consensus.

ADGRG7 vs MAN2B1 — PDAC

Explore this scatter interactively →