ADGRG7

Across TCGA patient cohorts, ADGRG7 mutation is significantly associated with the RNA expression of many other genes, with 3,207 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADGRG7-associated genes across cancer lineages are BNIP3P6, LINC01936, and C10orf143. Each is linked with ADGRG7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADGRG7-to-partner and partner-to-ADGRG7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P6 grouped by ADGRG7-low versus ADGRG7-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG7→partner) and Y-score (partner→ADGRG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BNIP3P6 →	+0.143	+7.057	<.001	.009	3	3
UCEC	LINC01936 →	-0.426	-2.978	<.001	<.001	3	3
UCEC	C10orf143 →	-0.232	-1.734	.005	.004	3	3
UCEC	ATP1B2 →	-0.630	-3.512	<.001	<.001	3	3
UCEC	PARP2 →	+0.345	+1.632	.001	<.001	3	3
UCEC	PSMB6 →	+0.315	+2.107	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,207 associations by consensus.

BNIP3P6 by ADGRG7 expression — BRCA

Explore this box plot interactively →