Across TCGA patient cohorts, ADGRG1 mutation is significantly associated with the RNA expression of many other genes, with 1,916 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADGRG1-associated genes across cancer lineages are ZNF25-DT, RN7SL66P, and NTAN1. Each is linked with ADGRG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRG1-to-partner and partner-to-ADGRG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRG1→partner) and Y-score (partner→ADGRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZNF25-DT →	+0.234	+6.409	<.001	<.001	3	2
LUAD	RN7SL66P →	+0.395	+5.217	<.001	.007	3	2
UCEC	NTAN1 →	+0.469	+2.254	<.001	.005	3	2
UCEC	HAAO →	-0.554	-3.437	.003	.005	3	2
UCEC	HSBP1P2 →	+0.357	+1.831	.008	.008	3	2
UCEC	SLC27A4 →	+0.399	+2.994	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,916 associations by consensus.

Exploration

ADGRG1 survival (RNA) · tumor vs normal (RNA) · all ADGRG1 data types