ADGRF4

Across TCGA patient cohorts, ADGRF4 protein abundance is significantly associated with the protein abundance of many other proteins, with 88 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ADGRF4-associated proteins across cancer lineages are MCM7_S500, SEPTIN8_S321, and TRUB1. Each is linked with ADGRF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRF4-to-partner and partner-to-ADGRF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRF4 versus MCM7_S500 in HNSC, with a Pearson correlation of 0.90.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRF4→partner) and Y-score (partner→ADGRF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MCM7_S500 →	+0.418	+0.408	.001	<.001	3	1
HNSC	SEPTIN8_S321 →	-1.546	-0.629	.009	.002	2	1
HNSC	TRUB1 →	+0.471	+0.541	<.001	<.001	2	1
HNSC	VPS54_S35 →	-1.017	-0.411	<.001	.001	2	1
HNSC	C11orf52_T30 →	+1.538	+0.376	.004	.003	2	1
HNSC	CLDN12_S231 →	+0.365	+0.442	.002	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

ADGRF4 vs MCM7_S500 — HNSC

Explore this scatter interactively →