ADGRB1

Across TCGA patient cohorts, ADGRB1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,881 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADGRB1-associated genes across cancer lineages are YPEL1, SNRPD3, and MAPK1. Each is linked with ADGRB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRB1-to-partner and partner-to-ADGRB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADGRB1 versus YPEL1 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRB1→partner) and Y-score (partner→ADGRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YPEL1 →	+0.521	+0.431	<.001	<.001	3	1
GBM	SNRPD3 →	+0.401	+0.471	<.001	<.001	3	1
GBM	MAPK1 →	+0.231	+0.368	.007	<.001	3	1
GBM	CYTH4 →	-0.715	-0.428	<.001	<.001	3	1
GBM	CARD10 →	+0.388	+0.402	.002	.004	3	1
GBM	SEZ6L →	+1.650	+0.620	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,881 associations by consensus.

ADGRB1 vs YPEL1 — GBM

Explore this scatter interactively →