ADGRB1

Across TCGA cell cohorts, ADGRB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,402 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADGRB1-associated GO terms across cancer lineages are Engulfment of apoptotic cell, Positive regulation of monoatomic ion transport, and Primary alcohol biosynthetic process. Each is linked with ADGRB1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ADGRB1-to-partner and partner-to-ADGRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Engulfment of apoptotic cell grouped by ADGRB1-low versus ADGRB1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRB1→partner) and Y-score (partner→ADGRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Engulfment of apoptotic cell →	-0.236	-1.689	<.001	<.001	3	8
PANCREAS	Positive regulation of monoatomic ion transport →	-0.079	-0.743	.002	.003	3	8
SOFT_TISSUE	Primary alcohol biosynthetic process →	-0.309	-1.872	<.001	<.001	3	7
OVARY	Negative regulation of gene expression, epigenetic →	+0.044	+1.132	.003	.005	3	7
LUNG_NSCLC_LUAD	Heart contraction →	-0.070	-0.526	.001	.009	1	9
LUNG_NSCLC_LUAD	Phagocytosis, recognition →	-0.782	-0.601	<.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,402 associations by consensus.

Engulfment of apoptotic cell by ADGRB1 expression — SOFT_TISSUE

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