ADGRA1-AS1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADGRA1-AS1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADGRA1-AS1-associated genes across cancer lineages are PKC-a_pS657 and PKC-a. Each is linked with ADGRA1-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADGRA1-AS1-to-partner and partner-to-ADGRA1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PKC-a_pS657 grouped by ADGRA1-AS1-low versus ADGRA1-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADGRA1-AS1→partner) and Y-score (partner→ADGRA1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPKC-a_pS657 →+0.463+2.820.048.03631
UCECPKC-a →+0.618+2.820.012.03531
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PKC-a_pS657 by ADGRA1-AS1 expression — UCEC

Box plot of PKC-a_pS657 in ADGRA1-AS1-low vs ADGRA1-AS1-high samples in UCEC.

Explore this box plot interactively →

Exploration