ADGRA1-AS1

Across TCGA pan-cancer cohorts, ADGRA1-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated ADGRA1-AS1 data layer compared with 2 for mutation status.

The strongest signal is observed in brain lower grade glioma (LGG), where higher ADGRA1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADGRA1-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and LIHC show a favorable association.

LGG, SKCM, and ACC are the cancer types where ADGRA1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.892	0.727	<.001	48	view →
SKCM	OS	Tertile	IV	0.297	0.777	<.001	45	view →
ACC	DFS	Quartile	III,IV	0.300	0.686	<.001	33	view →
UCEC	DFS	Tertile	All	0.835	0.904	.017	24	view →
LIHC	DFS	Tertile	III,IV	0.586	0.307	.014	24	view →
PAAD	DFS	Quartile	All	0.491	0.242	.003	16	view →
DLBC	OS	Tertile	II,III,IV	0.330	0.915	.006	15	view →
THCA	DFS	Tertile	IV	0.075	0.807	<.001	15	view →
OV	OS	Quartile	IV	0.330	0.821	.007	8	view →
HNSC	DFS	Tertile	III,IV	0.581	0.678	.038	6	view →
KIRP	DFS	Tertile	All	0.970	0.891	.032	5	view →
MESO	OS	Tertile	IV	0.363	0.631	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

ADGRA1-AS1–LGG (OS)

Open the LGG breakdown →