ADGRA1-AS1

Across TCGA pan-cancer cohorts, ADGRA1-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ADGRA1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ADGRA1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ADGRA1-AS1 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and LIHC are the cancer types where ADGRA1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADGRA1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−0.016	.001	6	view →
KIRC	All	All	−0.009	<.001	6	view →
LIHC	All	All	−0.009	<.001	3	view →
STAD	All	All	−0.013	.019	2	view →
LUAD	All	All	−0.003	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ADGRA1-AS1–KIRP

Open the KIRP breakdown →