ADCYAP1R1

Across TCGA cell cohorts, ADCYAP1R1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ADCYAP1R1-associated genes across cancer lineages are FAM47C, TMEM82, and KIAA1210. Each is linked with ADCYAP1R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADCYAP1R1-to-partner and partner-to-ADCYAP1R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47C grouped by ADCYAP1R1-low versus ADCYAP1R1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCYAP1R1→partner) and Y-score (partner→ADCYAP1R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	FAM47C →	+0.014	+4.017	<.001	.007	3	1
BLOOD_Lymphoma	TMEM82 →	+0.015	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	KIAA1210 →	+0.102	+3.843	.001	.007	3	1
BREAST	FAM236A →	+0.075	+4.781	<.001	.003	3	1
SKIN	C11orf53 →	+0.265	+2.882	.003	.005	3	1
SKIN	SPRR2G →	+0.166	+2.882	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

FAM47C by ADCYAP1R1 expression — OESOPHAGUS

Explore this box plot interactively →