ADCYAP1R1

Across TCGA pan-cancer cohorts, ADCYAP1R1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ADCYAP1R1 data layer compared with 7 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ADCYAP1R1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ADCYAP1R1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LGG show a favorable association.

BLCA, KIRP, and SKCM are the cancer types where ADCYAP1R1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.512	0.715	<.001	110	view →
KIRP	OS	Median	All	0.585	0.746	<.001	101	view →
SKCM	OS	Quartile	II,III,IV	0.316	0.546	<.001	92	view →
UCEC	OS	Tertile	All	0.918	0.816	.001	54	view →
UVM	OS	Median	III,IV	0.648	0.909	.001	50	view →
LGG	DFS	Median	All	0.804	0.669	<.001	41	view →
LUSC	DFS	Tertile	All	0.302	0.478	.002	30	view →
LUAD	DFS	Tertile	IV	0.528	0.869	.015	30	view →
ESCA	DFS	Quartile	III,IV	0.625	0.239	.006	27	view →
STAD	OS	Tertile	All	0.489	0.671	.002	24	view →
OV	DFS	Quartile	III,IV	0.602	0.463	.005	20	view →
COAD	DFS	Quartile	All	0.576	0.746	.003	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ADCYAP1R1–BLCA (OS)

Open the BLCA breakdown →