ADCY4

Across TCGA patient cohorts, ADCY4 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,910 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ADCY4-associated proteins across cancer lineages are KANK3, NID2, and ILK. Each is linked with ADCY4 in more than 8 cancer types. Because this analysis shows association rather than direction, both ADCY4-to-partner and partner-to-ADCY4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCY4 versus KANK3 in CCRCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY4→partner) and Y-score (partner→ADCY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KANK3 →	+0.676	+0.859	<.001	<.001	3	9
GBM	NID2 →	+0.675	+0.540	<.001	<.001	3	8
BRCA	ILK →	+0.501	+1.008	<.001	<.001	3	8
OV	LAMA4 →	+0.660	+0.694	<.001	<.001	3	8
GBM	LUM →	+1.201	+0.522	<.001	<.001	3	8
CCRCC	RASIP1 →	+0.650	+1.045	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,910 associations by consensus.

ADCY4 vs KANK3 — CCRCC

Explore this scatter interactively →