ADCY4

Across TCGA patient cohorts, ADCY4 protein abundance is significantly associated with the RNA expression of many other genes, with 411 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADCY4-associated genes across cancer lineages are CHADL, SLC25A14, and GLA. Each is linked with ADCY4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADCY4-to-partner and partner-to-ADCY4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADCY4 versus CHADL in LSCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY4→partner) and Y-score (partner→ADCY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CHADL →	+0.855	+0.599	<.001	.006	3	1
LSCC	SLC25A14 →	-0.505	-0.628	.009	.006	3	1
LSCC	GLA →	-0.565	-0.526	.006	.004	3	1
LSCC	CYTH2 →	+0.476	+0.646	.001	.003	3	1
LSCC	GCLC →	-1.888	-0.542	.001	.001	3	1
LSCC	GPN3 →	-0.467	-0.487	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 411 associations by consensus.

ADCY4 vs CHADL — LSCC

Explore this scatter interactively →