ADCY4

Across TCGA cell cohorts, ADCY4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,398 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADCY4-associated GO terms across cancer lineages are T cell mediated cytotoxicity, Regulation of myoblast fusion, and Regulation of CD8-positive, alpha-beta T cell extravasation. Each is linked with ADCY4 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADCY4-to-partner and partner-to-ADCY4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell mediated cytotoxicity grouped by ADCY4-low versus ADCY4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY4→partner) and Y-score (partner→ADCY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	T cell mediated cytotoxicity →	+0.238	+0.906	<.001	<.001	3	10
LUNG_SCLC	Regulation of myoblast fusion →	+0.097	+0.497	<.001	<.001	3	9
LUNG_SCLC	Regulation of CD8-positive, alpha-beta T cell extravasation →	-0.478	-0.506	<.001	<.001	3	9
STOMACH	Regulation of protein localization to plasma membrane →	+0.092	+0.777	.001	.007	3	8
OVARY	Response to steroid hormone →	+0.073	+0.423	<.001	.006	3	8
OVARY	Striated muscle contraction →	+0.064	+0.513	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,398 associations by consensus.

T cell mediated cytotoxicity by ADCY4 expression — STOMACH

Explore this box plot interactively →