ADCY10P1

Across TCGA patient cohorts, ADCY10P1 mutation is significantly associated with the RNA expression of many other genes, with 1,225 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADCY10P1-associated genes across cancer lineages are RNU6-246P, TRAJ53, and CLUHP5. Each is linked with ADCY10P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADCY10P1-to-partner and partner-to-ADCY10P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-246P grouped by ADCY10P1-low versus ADCY10P1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADCY10P1→partner) and Y-score (partner→ADCY10P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-246P →	+0.485	+5.306	<.001	.006	3	1
CESC	TRAJ53 →	+0.715	+5.812	<.001	.003	3	1
CESC	CLUHP5 →	+0.062	+5.812	<.001	.003	3	1
CESC	UBE2V1P11 →	+0.159	+5.103	<.001	.008	3	1
UCEC	IGKV1OR2-118 →	+0.304	+2.496	<.001	<.001	3	1
UCEC	IGHV3OR16-13 →	+0.512	+2.041	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,225 associations by consensus.

RNU6-246P by ADCY10P1 expression — CESC

Explore this box plot interactively →