ADCY10P1

Across TCGA pan-cancer cohorts, ADCY10P1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ADCY10P1 data layer compared with 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ADCY10P1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADCY10P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, BLCA, and READ are the cancer types where ADCY10P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.466	0.290	<.001	116	view →
BLCA	DFS	Median	II,III,IV	0.387	0.292	.004	63	view →
READ	OS	Quartile	II,III,IV	0.783	0.393	<.001	51	view →
THYM	DFS	Median	III,IV	1.000	0.216	<.001	42	view →
LIHC	DFS	Tertile	All	0.414	0.636	<.001	38	view →
KIRC	DFS	Tertile	II,III,IV	0.387	0.640	.001	36	view →
UCS	OS	Tertile	II,III,IV	0.685	0.217	.001	36	view →
KICH	DFS	Median	III,IV	0.373	1.000	.008	36	view →
LAML	DFS	Median	All	0.533	0.261	.013	24	view →
UVM	DFS	Median	III,IV	0.283	0.758	.007	23	view →
ACC	DFS	Tertile	II,III,IV	0.235	0.681	.011	20	view →
PAAD	OS	Median	All	0.605	0.364	.019	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ADCY10P1–HNSC (OS)

Open the HNSC breakdown →