ADCY10P1

Across TCGA pan-cancer cohorts, ADCY10P1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ADCY10P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ADCY10P1 RNA is repressed in tumor relative to normal tissue. In most cancer types ADCY10P1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LIHC are the cancer types where ADCY10P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ADCY10P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.049	<.001	10	view →
THCA	Female	II,III,IV	−0.872	<.001	9	view →
LIHC	All	II,III,IV	+0.587	<.001	8	view →
BRCA	Female	All	−0.681	<.001	6	view →
COAD	All	All	+0.344	<.001	5	view →
CHOL	All	All	+1.607	<.001	3	view →
STAD	All	All	+0.418	.009	3	view →
LUSC	Male	All	+0.284	.020	2	view →
READ	Female	All	+0.866	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ADCY10P1–KICH

Open the KICH breakdown →