ADAT1

Across TCGA patient cohorts, ADAT1 mutation is significantly associated with the RNA expression of many other genes, with 1,147 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAT1-associated genes across cancer lineages are BCRP6, LINC01851, and RNU6-886P. Each is linked with ADAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAT1-to-partner and partner-to-ADAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCRP6 grouped by ADAT1-low versus ADAT1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAT1→partner) and Y-score (partner→ADAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BCRP6 →	+0.068	+3.686	.001	.005	3	2
SKCM	LINC01851 →	+0.035	+4.039	<.001	.009	3	2
COAD	RNU6-886P →	+0.466	+3.789	<.001	.004	3	2
UCEC	H2AZ1 →	+0.541	+2.601	.005	.006	3	2
UCEC	TRABD →	+0.422	+3.732	.008	<.001	3	2
UCEC	GTSE1 →	+0.642	+3.470	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,147 associations by consensus.

BCRP6 by ADAT1 expression — COAD

Explore this box plot interactively →