ADAMTS9

Across TCGA patient cohorts, ADAMTS9 protein abundance is significantly associated with the RNA expression of many other genes, with 786 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAMTS9-associated genes across cancer lineages are GUCY2F, NHSL2, and CACNA1F. Each is linked with ADAMTS9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAMTS9-to-partner and partner-to-ADAMTS9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS9 versus GUCY2F in UCEC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS9→partner) and Y-score (partner→ADAMTS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GUCY2F →	-0.695	-0.570	.003	.004	3	2
UCEC	NHSL2 →	-0.813	-0.435	.006	.004	3	2
GBM	CACNA1F →	-0.223	-0.725	<.001	<.001	3	1
GBM	PLS3 →	-0.903	-0.621	.002	.004	3	1
GBM	CCNE1 →	-0.597	-0.627	.006	.003	3	1
GBM	HIBADH →	-0.550	-0.794	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 786 associations by consensus.

ADAMTS9 vs GUCY2F — UCEC

Explore this scatter interactively →