ADAMTS9

Across TCGA cell cohorts, ADAMTS9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,732 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ADAMTS9-associated GO terms across cancer lineages are Protein activation cascade, Positive regulation of leukocyte differentiation, and Positive regulation of hemopoiesis. Each is linked with ADAMTS9 in more than 7 cancer types. Because this analysis shows association rather than direction, both ADAMTS9-to-partner and partner-to-ADAMTS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein activation cascade grouped by ADAMTS9-low versus ADAMTS9-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS9→partner) and Y-score (partner→ADAMTS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein activation cascade →	+0.309	+1.482	<.001	<.001	3	8
LARGE_INTESTINE	Positive regulation of leukocyte differentiation →	+0.032	+0.841	.007	.001	3	7
LARGE_INTESTINE	Positive regulation of hemopoiesis →	+0.032	+0.841	.007	.001	3	7
LARGE_INTESTINE	Substrate adhesion-dependent cell spreading →	+0.130	+1.357	<.001	.001	3	7
CNS	Sympathetic ganglion development →	+0.213	+1.232	<.001	.001	3	7
LARGE_INTESTINE	Regulation of plasminogen activation →	+0.136	+1.126	.008	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,732 associations by consensus.

Protein activation cascade by ADAMTS9 expression — LARGE_INTESTINE

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