ADAMTS9

Across TCGA cell cohorts, ADAMTS9 mutation is significantly associated with the RNA expression of many other genes, with 718 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADAMTS9-associated genes across cancer lineages are OR52L1, CCDC195, and OR4N4. Each is linked with ADAMTS9 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAMTS9-to-partner and partner-to-ADAMTS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52L1 grouped by ADAMTS9-low versus ADAMTS9-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS9→partner) and Y-score (partner→ADAMTS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR52L1 →	+0.020	+4.977	<.001	.002	3	3
BLOOD_Myeloma	CCDC195 →	+0.043	+3.285	.004	.009	3	2
PANCREAS	OR4N4 →	+0.039	+5.000	<.001	.006	3	2
LARGE_INTESTINE	VAPA →	+0.557	+3.459	<.001	<.001	3	2
SKIN	CLUAP1 →	+0.607	+3.064	.001	.009	3	2
LARGE_INTESTINE	C1QBP →	+0.636	+2.584	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 718 associations by consensus.

OR52L1 by ADAMTS9 expression — SOFT_TISSUE

Explore this box plot interactively →