ADAMTS3

Across TCGA patient cohorts, ADAMTS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,932 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADAMTS3-associated proteins across cancer lineages are FMNL3, PALM2AKAP2, and NES. Each is linked with ADAMTS3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ADAMTS3-to-partner and partner-to-ADAMTS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS3 versus FMNL3 in COAD, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS3→partner) and Y-score (partner→ADAMTS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FMNL3 →	+0.450	+0.299	<.001	<.001	3	7
UCEC	PALM2AKAP2 →	+0.357	+0.582	<.001	<.001	3	7
UCEC	NES →	+0.517	+0.456	<.001	.004	3	7
CCRCC	EFEMP1 →	+0.838	+0.639	.003	.003	3	6
UCEC	FERMT2 →	+0.712	+0.499	<.001	.002	3	6
CCRCC	VCAN →	+1.052	+0.598	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,932 associations by consensus.

ADAMTS3 vs FMNL3 — COAD

Explore this scatter interactively →