ADAMTS14

Across TCGA patient cohorts, ADAMTS14 protein abundance is significantly associated with the RNA expression of many other genes, with 790 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADAMTS14-associated genes across cancer lineages are ZDHHC15, PTGDS, and SOD3. Each is linked with ADAMTS14 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAMTS14-to-partner and partner-to-ADAMTS14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAMTS14 versus ZDHHC15 in HNSC, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS14→partner) and Y-score (partner→ADAMTS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZDHHC15 →	-0.715	-1.766	.002	<.001	3	1
HNSC	PTGDS →	-0.767	-1.462	.004	.001	3	1
HNSC	SOD3 →	-1.239	-1.250	.004	.007	3	1
HNSC	ELMOD1 →	-0.446	-1.588	.001	.006	3	1
HNSC	PPM1H →	-1.468	-1.616	.005	.002	3	1
HNSC	ACADL →	-0.951	-1.676	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 790 associations by consensus.

ADAMTS14 vs ZDHHC15 — HNSC

Explore this scatter interactively →